KRAS G12C inhibitor 16( —— )

Catalog No. M32985 CAS No. 2349392-79-4

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HNMR

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Product Name

KRAS G12C inhibitor 16
Note

Research use only, not for human use.
Brief Description

KRAS G12C inhibitor 16 is a potent inhibitor of KRAS G12C.
Description

KRAS G12C inhibitor 16 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 39, has an IC50 of 97 nM.
In Vitro

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In Vivo

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Synonyms

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Pathway

Others
Target

Other Targets
Recptor

Kras
Research Area

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Indication

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CAS Number

2349392-79-4
Formula Weight

453.89
Molecular Formula

C24H21ClFN3O3
Purity

>98% (HPLC)
Solubility

——
SMILES

CC1=C2C(C=3N4[C@](CN(C(C=C)=O)CC4)(COC3C=N2)[H])=CC(Cl)=C1C5=C(F)C=CC=C5O
Chemical Name

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1. Jason Grant Kettle, et al. Tetracyclic compounds as inhibitors of g12c mutant ras protein, for use as anti-cancer agents. WO2019110751A1.

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